Details of the Drug

General Information of Drug (ID: DMCGWBJ)

Drug Name
Epigallocatechin gallate
Synonyms
(-)-Epigallocatechin gallate; EGCG; 989-51-5; Epigallocatechin 3-gallate; Epigallocatechin-3-gallate; Tea catechin; (-)-Epigallocatechin-3-o-gallate; Teavigo; Epigallocatechin-3-monogallate; (-)-Epigallocatechol gallate; (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate; Catechin deriv; UNII-BQM438CTEL; Green tea extract; CCRIS 3729; (-)-epigallocatechin 3-gallate; C22H18O11; BQM438CTEL; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl; EGCG analogs; EGCG, Anagen; Epigallocatechin gallate analogs, Anagen; Epigallocatechin gallate, Anagen; GTPs,Anagen; Green tea polyphenols, Anagen; EPIGALOCATECHIN GALLATE
Indication
Disease Entry ICD 11 Status REF
Hepatic fibrosis DB93.0 Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 458.4
Logarithm of the Partition Coefficient (xlogp) 1.2
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 8
Hydrogen Bond Acceptor Count (hbondacc) 11
Chemical Identifiers
Formula
C22H18O11
IUPAC Name
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Canonical SMILES
C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
InChI
InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
InChIKey
WMBWREPUVVBILR-WIYYLYMNSA-N
Cross-matching ID
PubChem CID
65064
ChEBI ID
CHEBI:4806
CAS Number
989-51-5
UNII
BQM438CTEL
DrugBank ID
DB12116
TTD ID
D0U2BH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty acid synthase (FASN) TT7AOUD FAS_HUMAN Inhibitor [2]
Human immunodeficiency virus Reverse transcriptase (HIV RT) TT84ETX POL_HV1B1 Inhibitor [3]
Matrix metalloproteinase-14 (MMP-14) TTJ4QE7 MMP14_HUMAN Inhibitor [4]
Matrix metalloproteinase-2 (MMP-2) TTLM12X MMP2_HUMAN Inhibitor [4]
Neutrophil elastase (NE) TTPLTSQ ELNE_HUMAN Inhibitor [5]
Plasmodium Beta-hydroxyacyl-ACP dehydratase (Malaria FabZ) TTHPFTS Q965D7_PLAFA Inhibitor [2]
Plasmodium Enoyl-ACP reductase (Malaria fabI) TTNX2CS Q965D5_PLAFA Inhibitor [6]
Plasmodium Oxoacyl-[acyl-carrier protein] reductase (Malaria fabG) TTBE4IR Q965D6_PLAFA Inhibitor [2]
Squalene monooxygenase (SQLE) TTE14XG ERG1_HUMAN Inhibitor [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1) OTJISZOX PLCE1_HUMAN Gene/Protein Processing [8]
10 kDa heat shock protein, mitochondrial (HSPE1) OT7JSZLB CH10_HUMAN Gene/Protein Processing [9]
2'-5'-oligoadenylate synthase 2 (OAS2) OT64CCTM OAS2_HUMAN Gene/Protein Processing [10]
2'-5'-oligoadenylate synthase 3 (OAS3) OT6E5FYS OAS3_HUMAN Gene/Protein Processing [10]
2-iminobutanoate/2-iminopropanoate deaminase (RIDA) OTW4098I RIDA_HUMAN Gene/Protein Processing [8]
26S proteasome regulatory subunit 6B (PSMC4) OTS3XN41 PRS6B_HUMAN Gene/Protein Processing [9]
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) OTRT3F3U HMDH_HUMAN Gene/Protein Processing [10]
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (SRD5A2) OTTG0NFD S5A2_HUMAN Gene/Protein Processing [11]
5,6-dihydroxyindole-2-carboxylic acid oxidase OTRK49R4 TYRP1_HUMAN Gene/Protein Processing [11]
7-dehydrocholesterol reductase (DHCR7) OTLILBUI DHCR7_HUMAN Gene/Protein Processing [10]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 122 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 4.0122 6.3915 3.9689 28.2099
MEC1 CTRP2 7.591 8.3569 7.494 4.5902
JM1 CTRP2 7.6115 8.2467 7.5501 4.3239
DoHH2 CTRP2 -1.1825 2.3048 -1.191 62.3643
Ku812 CTRP2 1.2594 8.7417 0.4768 47.1059
EM-2 CTRP2 2.2443 7.7369 1.8252 40.8429
Ri-1 CTRP2 2.2991 6.8668 2.072 40.0697
KMS-28BM CTRP2 2.3113 5.1047 2.2873 39.459
SU-DHL-10 CTRP2 2.3226 8.4242 1.7288 40.7111
SK-MM-2 CTRP2 2.9445 4.6238 2.943 35.1758
SUP-T11 CTRP2 3.4491 4.7899 3.4486 31.8141
RS4;11 CTRP2 3.5391 4.6818 3.5389 31.2142
Hs 611.T CTRP2 3.5944 5.3054 3.5903 30.859
LAMA-84 CTRP2 3.5952 8.8101 3.0021 32.7398
HPB-ALL CTRP2 3.613 4.1402 3.613 30.7219
SU-DHL-6 CTRP2 3.6837 5.5622 3.6753 30.2789
ALL-SIL CTRP2 3.6876 4.3874 3.6876 30.2252
TALL-1 [Human adult T-ALL] CTRP2 3.7156 4.8392 3.7154 30.0393
OPM-2 CTRP2 3.7393 4.387 3.7393 29.8807
OCI-Ly3 CTRP2 3.7819 4.3028 3.7819 29.5972
KMS-12-BM CTRP2 3.8138 4.4881 3.8138 29.3853
NU-DHL-1 CTRP2 3.8168 4.6241 3.8168 29.3652
SU-DHL-8 CTRP2 3.8618 4.6225 3.8618 29.0657
697 CTRP2 3.9324 4.6356 3.9324 28.5961
MOLT-16 CTRP2 4.0005 4.7807 4.0005 28.1428
KMS-34 CTRP2 4.0584 4.8827 4.0583 27.7575
Daudi CTRP2 4.1219 5.0125 4.1219 27.3347
NCO2 CTRP2 4.1862 5.8156 4.1799 26.9274
Granta-519 CTRP2 4.2221 5.2615 4.2219 26.6684
MHH-CALL-4 CTRP2 4.2982 5.7313 4.295 26.1717
Kasumi-2 CTRP2 4.3028 6.6814 4.2467 26.3194
SUP-T1 CTRP2 4.3035 5.7058 4.3008 26.1349
MV4-11 CTRP2 4.3278 16.1884 0.6653 35.8741
MOLP-8 CTRP2 4.4741 5.2762 4.4741 24.9905
EHEB CTRP2 4.4899 5.5793 4.4893 24.8871
KMS-26 CTRP2 4.5126 5.1636 4.5126 24.7338
KMS-27 CTRP2 4.5174 5.116 4.5174 24.7022
NALM-6 CTRP2 4.5274 5.3432 4.5274 24.6355
KE-37 CTRP2 4.5348 5.2533 4.5348 24.5865
PF-382 CTRP2 4.5675 5.7975 4.5659 24.3741
KE-97 CTRP2 4.5741 5.8267 4.5722 24.331
HT CTRP2 4.6006 5.0889 4.6006 24.1487
HEL CTRP2 4.6007 5.1167 4.6007 24.1475
WSU-DLCL2 CTRP2 4.6049 5.0696 4.6049 24.1197
JVM-3 CTRP2 4.6127 5.327 4.6127 24.0679
Ki-JK CTRP2 4.6188 5.662 4.6183 24.0288
A4/Fukuda CTRP2 4.6254 5.2636 4.6254 23.9833
KHM-1B CTRP2 4.6364 5.2722 4.6364 23.9101
NCI-H929 CTRP2 4.6639 6.4491 4.6439 23.7942
KMS-20 CTRP2 4.6705 5.1756 4.6705 23.6832
Raji CTRP2 4.6884 5.1691 4.6884 23.5638
MM1.S CTRP2 4.6932 5.2218 4.6932 23.5319
MOLP-2 CTRP2 4.6942 5.3665 4.6942 23.5257
DND-41 CTRP2 4.6974 5.4014 4.6974 23.5044
Karpas-299 CTRP2 4.7074 5.1951 4.7074 23.4374
HH [Human lymphoma] CTRP2 4.7095 5.7342 4.709 23.425
MOLT-13 CTRP2 4.7096 5.2865 4.7096 23.4227
M-07e CTRP2 4.7291 5.2313 4.7291 23.2928
ST486 CTRP2 4.741 5.4532 4.741 23.2142
HDLM-2 CTRP2 4.8059 6.5499 4.7849 22.8523
Reh CTRP2 4.8107 5.4117 4.8107 22.7498
Mono-Mac-6 CTRP2 4.9429 13.965 2.3108 30.4862
SU-DHL-4 CTRP2 4.9438 5.9057 4.9434 21.8655
NU-DUL-1 CTRP2 5.1465 6.2302 5.1446 20.5213
ME1 CTRP2 5.1663 7.0453 5.12 20.5393
PL21 CTRP2 5.2117 7.0408 5.1685 20.2266
KMS-18 CTRP2 5.4645 7.5992 5.3577 18.7636
KM-H2 CTRP2 5.4776 8.9613 4.9986 20.0205
RPMI-8402 CTRP2 5.5818 8.0415 5.389 18.2867
RPMI-8226 CTRP2 5.7086 8.4573 5.4128 17.8161
JURL-MK1 CTRP2 5.7982 6.9721 5.7871 16.2146
L-363 CTRP2 5.8346 7.4194 5.7842 16.106
BV-173 CTRP2 5.9276 7.7852 5.8231 15.6746
OCI-AML-2 CTRP2 6.068 7.6172 6.0051 14.5956
KMS-11 CTRP2 6.1355 7.8273 6.0401 14.2601
NB4 CTRP2 6.3995 7.5517 6.3684 12.2804
Toledo CTRP2 6.4214 10.4794 5.3861 15.9422
L-540 CTRP2 6.4975 7.875 6.4228 11.7792
SR CTRP2 6.5142 7.9179 6.4324 11.6931
THP-1 CTRP2 6.6134 8.2296 6.4657 11.2681
AMO1 CTRP2 6.7149 8.3784 6.5335 10.7159
MOLM-6 CTRP2 6.7714 8.585 6.5285 10.5675
KYO-1 CTRP2 6.7772 7.705 6.7509 9.7506
MOLM-13 CTRP2 6.7829 8.4399 6.5885 10.312
MOLM-16 CTRP2 6.8292 8.2267 6.702 9.7597
MC116 CTRP2 6.8388 8.2412 6.7085 9.7075
KMM-1 CTRP2 6.9964 21.3691 0.6054 29.4826
KCL-22 CTRP2 7.0399 15.2359 3.6911 20.8782
AML-193 CTRP2 7.1831 8.079 7.1248 7.161
Kasumi-1 CTRP2 7.2015 8.2714 7.0957 7.2088
SKM-1 CTRP2 7.2169 9.684 6.5493 9.2821
Mono-Mac-1 CTRP2 7.2566 9.9113 6.4846 9.4435
RCH-ACV CTRP2 7.2683 11.1967 5.8842 11.8642
NOMO-1 CTRP2 7.3103 8.4055 7.1732 6.6009
P3HR-1 CTRP2 7.3334 12.5841 5.2664 14.2387
U-937 CTRP2 7.4333 8.4218 7.3012 5.7665
DEL CTRP2 7.4538 11.4252 5.9464 11.1872
KO52 CTRP2 7.5101 8.0229 7.4896 4.8533
Jurkat CTRP2 7.5102 13.4942 4.9756 15.0186
SUP-HD1 CTRP2 7.5499 9.1607 7.1222 6.1466
GDM-1 CTRP2 7.55 9.5618 6.9372 6.8924
OCI-AML-3 CTRP2 7.5996 8.1575 7.5602 4.3241
LP-1 CTRP2 7.6057 8.3346 7.5173 4.461
HD-MY-Z CTRP2 7.6231 8.1081 7.5964 4.1229
RPMI-6666 CTRP2 7.6464 8.255 7.5858 4.0891
REC-1 CTRP2 7.684 14.6856 4.5359 16.3672
SIG-M5 CTRP2 7.6851 8.1416 7.6568 3.7163
EJM CTRP2 7.6977 8.5104 7.5538 4.0601
JJN-3 CTRP2 7.7279 8.1891 7.6925 3.4568
OCI-Ly19 CTRP2 7.7465 8.4439 7.6313 3.628
TF-1 CTRP2 7.7663 8.155 7.7421 3.1616
HL-60 CTRP2 7.7839 8.1884 7.7537 3.0661
JeKo-1 CTRP2 7.8465 8.3974 7.7559 2.8734
OCI-M1 CTRP2 7.9152 8.4497 7.8084 2.4817
CMK CTRP2 7.9622 8.4297 7.8661 2.1304
K-562 CTRP2 8.0092 8.7094 7.7877 2.3244
SUP-B15 CTRP2 8.0281 8.8725 7.7275 2.5273
OCI-Ly10 CTRP2 8.228 9.3947 7.6452 2.4525
MHH-CALL-3 CTRP2 8.2579 14.406 5.1644 12.7269
Karpas-620 CTRP2 8.2648 9.3131 7.7164 2.0835
OCI-AML-5 CTRP2 8.3004 16.0912 4.3571 15.7893
P31/FUJ CTRP2 9.4824 20.3751 3.1662 17.7474
⏷ Show the Full List of 122 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 5.8416 7.8367 5.7193 16.3093
TE15 CTRP2 7.3198 8.7081 7.0744 6.9457
COLO 680N CTRP2 4.5555 5.1354 4.5555 24.4489
KYSE-410 CTRP2 6.0579 7.9778 5.9232 14.9144
TE-6 CTRP2 6.2509 8.6556 5.9403 14.271
TE-10 CTRP2 6.3848 9.3212 5.8401 14.2689
TE-9 CTRP2 7.3091 10.5403 6.2391 10.3153
KYSE-140 CTRP2 7.3797 9.461 6.8145 7.809
KYSE-70 CTRP2 7.417 9.7418 6.7221 8.089
TE-1 CTRP2 7.4904 9.8518 6.7422 7.8294
TE-4 CTRP2 7.5191 8.7493 7.2691 5.6476
TE-11 CTRP2 7.542 8.8826 7.2369 5.7121
TE-14 CTRP2 7.5453 8.8425 7.2575 5.6227
KYSE-520 CTRP2 7.6905 8.9777 7.3468 4.892
OE21 CTRP2 7.7206 8.3374 7.6412 3.6655
OE33 CTRP2 7.7248 14.2375 4.7948 15.2763
KYSE-180 CTRP2 8.0794 11.9475 6.2435 8.6269
KYSE-450 CTRP2 8.1112 9.0744 7.7044 2.4401
KYSE-30 CTRP2 8.137 9.1777 7.6758 2.5057
EC-GI-10 CTRP2 8.1487 9.1796 7.6851 2.4426
KYSE-510 CTRP2 8.176 9.53 7.5337 3.0223
KYSE-150 CTRP2 8.2647 9.3441 7.7008 2.1492
OE19 CTRP2 13.102 28.0294 2.0363 15.6178
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.674 14.876 4.4322 16.7837
SNU-410 CTRP2 5.6042 10.1773 4.6698 20.8886
QGP-1 CTRP2 5.8265 8.0298 5.6586 16.5712
YAPC CTRP2 6.1069 7.3545 6.0805 14.2117
PaTu 8988s CTRP2 6.1614 8.1146 6.0027 14.312
Panc 05.04 CTRP2 6.2259 8.0237 6.0954 13.7823
TCC-Pan2 CTRP2 6.2287 7.5688 6.1844 13.4625
KP-3 CTRP2 6.2316 11.3978 4.7784 18.8036
PK-59 CTRP2 6.4347 7.4231 6.4184 11.9959
PaTu 8902 CTRP2 6.6262 7.1272 6.6258 10.668
BxPC-3 CTRP2 6.6951 11.5674 5.1564 16.1659
SU.86.86 CTRP2 6.8074 9.0884 6.3805 11.0263
L3.3 CTRP2 6.8986 8.7489 6.608 9.9038
HPAC CTRP2 7.3854 16.3778 3.4317 20.9933
PaTu 8988t CTRP2 7.4202 12.522 5.376 13.6021
MIA PaCa-2 CTRP2 7.4411 8.211 7.374 5.4766
HuP-T4 CTRP2 7.486 9.0944 7.0869 6.4507
KP-4 CTRP2 7.501 8.1765 7.4481 5.0277
PK-45H CTRP2 7.527 8.2885 7.4458 4.9571
HuP-T3 CTRP2 7.5459 8.2761 7.4701 4.8119
DAN-G CTRP2 7.5761 31.246 -3.8281 35.1402
Panc 04.03 CTRP2 7.5924 17.7508 2.9276 22.1798
Panc 03.27 CTRP2 7.6031 8.1121 7.5739 4.265
CFPAC-1 CTRP2 7.6261 13.6108 5.0204 14.5918
AsPC-1 CTRP2 7.6606 8.3295 7.5786 4.0732
PSN1 CTRP2 7.6937 8.318 7.6182 3.8297
Panc 08.13 CTRP2 7.6988 8.3032 7.6285 3.7766
Capan-2 CTRP2 7.7183 8.3979 7.6178 3.7591
SW1990 CTRP2 7.7704 8.4775 7.644 3.513
Hs 766T CTRP2 7.8082 9.3124 7.3062 4.7696
SNU-213 CTRP2 8.0725 8.6778 7.8637 1.8637
Panc 02.03 CTRP2 8.1226 8.8488 7.8263 1.9068
SUIT-2 CTRP2 8.2148 11.154 6.7545 6.2179
Capan-1 CTRP2 8.2602 9.6702 7.5341 2.8575
KP-2 CTRP2 8.2986 9.66 7.5705 2.6329
HPAF-II CTRP2 10.4849 22.8569 2.6992 17.514
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 7.1623 16.0277 3.4084 21.5659
Hs 852.T CTRP2 4.1578 5.9892 4.1453 27.1371
RPMI-7951 CTRP2 4.6077 5.231 4.6077 24.101
MDA-MB-435S CTRP2 4.6145 5.055 4.6145 24.056
WM793 CTRP2 5.1315 6.1197 5.1305 20.6182
SK-MEL-30 CTRP2 5.2442 6.9152 5.2148 19.9636
LOX-IMVI CTRP2 6.1838 8.1031 6.03 14.1453
WM1799 CTRP2 6.6179 8.7333 6.3111 11.8239
SK-MEL-1 CTRP2 7.0298 14.5547 4.0184 19.7383
G-361 CTRP2 7.1362 8.7853 6.8489 8.3194
A-375 CTRP2 7.3425 10.7579 6.1666 10.5345
IPC-298 CTRP2 7.3613 13.9574 4.6129 16.7662
COLO 829 CTRP2 7.3641 14.2587 4.466 17.3237
Hs 936.T CTRP2 7.3646 11.024 6.0588 10.9262
A101D CTRP2 7.4329 9.8446 6.6895 8.1824
WM983B CTRP2 7.4538 13.0258 5.1573 14.4137
COLO 792 CTRP2 7.4626 8.7367 7.2147 6.0124
A2058 CTRP2 7.4924 8.1316 7.4495 5.0493
COLO 800 CTRP2 7.5237 8.2349 7.4576 4.9242
Hs 944.T CTRP2 7.5542 10.7679 6.3609 9.249
RVH-421 CTRP2 7.5738 8.1862 7.5251 4.5288
Hs 294T CTRP2 7.611 8.1082 7.5833 4.2071
K029AX CTRP2 7.6172 8.134 7.5846 4.1829
HT-144 CTRP2 7.6728 8.2158 7.6255 3.8658
WM88 CTRP2 7.7343 8.2254 7.69 3.4461
SK-MEL-24 CTRP2 7.7714 9.0831 7.379 4.5612
SK-MEL-3 CTRP2 7.7822 8.6759 7.5743 3.7521
IGR-1 CTRP2 7.7938 8.3624 7.7119 3.1891
SK-MEL-31 CTRP2 7.7943 9.9056 7.0055 6.0414
WT2-iPS CTRP2 7.8277 8.6604 7.6279 3.4212
UACC-257 CTRP2 7.8574 8.3859 7.7718 2.7821
MeWo CTRP2 7.8574 9.425 7.2987 4.6862
Hs 895.T CTRP2 7.8681 9.3745 7.3333 4.5192
WM266-4 CTRP2 7.8872 8.7277 7.6584 3.1472
IGR-39 CTRP2 7.9121 8.4029 7.8238 2.4307
HMCB CTRP2 7.9158 8.6911 7.7037 2.8936
WM115 CTRP2 7.9491 9.2245 7.4822 3.7198
CJM [Human melanoma] CTRP2 7.9935 8.7434 7.7563 2.4898
SK-MEL-5 CTRP2 8.1139 11.4681 6.5125 7.4316
UACC-62 CTRP2 8.2793 9.6822 7.5438 2.781
Hs 839.T CTRP2 8.2812 9.9878 7.3926 3.412
SK-MEL-28 CTRP2 8.2831 10.6277 7.0743 4.7447
SK-MEL-2 CTRP2 9.5613 10.56 7.9018 0.1571
IGR-37 CTRP2 10.5217 22.3709 2.9658 16.6353
Mel JuSo CTRP2 10.8745 26.8831 1.0043 21.4928
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SiMa CTRP2 3.3426 5.3825 3.333 32.5533
SK-N-DZ CTRP2 3.4508 5.6093 3.4357 31.8516
CHP-126 CTRP2 4.5965 5.2964 4.5965 24.1758
Kelly CTRP2 4.6104 5.8472 4.6086 24.0894
SK-N-FI CTRP2 4.737 5.2791 4.737 23.2404
NB1 CTRP2 5.6828 7.1816 5.6509 17.0529
KP-N-SI9s CTRP2 6.2555 7.4323 6.2292 13.2225
KP-N-YN CTRP2 6.6138 9.2473 6.1121 12.5919
SK-N-SH CTRP2 6.8405 10.8374 5.6422 13.8664
SK-N-BE(2) CTRP2 6.9864 10.0952 6.1305 11.5411
CHP-212 CTRP2 7.4012 8.5349 7.2268 6.1378
SK-N-AS CTRP2 7.5907 8.1897 7.5427 4.414
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 4.4993 5.6807 4.4983 24.8259
SNU-1196 CTRP2 4.6082 5.1256 4.6082 24.0977
HuH-28 CTRP2 6.0546 8.2938 5.8379 15.2305
SNU-308 CTRP2 7.6901 9.935 6.8936 6.7401
SNU-869 CTRP2 7.9095 8.4448 7.8044 2.5128
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJSA-1 CTRP2 4.3095 5.9658 4.3012 26.1138
A-673 CTRP2 4.6235 5.1157 4.6235 23.9959
MHH-ES-1 CTRP2 5.2019 6.7082 5.1855 20.2013
SK-ES-1 CTRP2 6.2127 7.4708 6.1798 13.5299
TC71 CTRP2 7.3257 12.1208 5.487 13.3596
CAL-78 CTRP2 7.4417 8.6188 7.2389 5.9771
SK-N-MC CTRP2 7.4595 7.9885 7.4406 5.1846
HOS CTRP2 7.5345 8.1618 7.4882 4.7815
SW1353 CTRP2 7.5484 12.2931 5.6051 12.3854
MG-63 CTRP2 7.5753 8.8868 7.2695 5.4962
G-292 clone A141B1 CTRP2 7.5956 8.2376 7.5353 4.4256
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KPL-1 CTRP2 4.5233 4.8997 4.5233 24.6631
CAL-148 CTRP2 4.585 5.9868 4.5808 24.2662
CAL-51 CTRP2 4.782 6.1027 4.7781 22.9539
HCC1937 CTRP2 4.8436 9.5967 4.0878 25.1989
HCC1143 CTRP2 5.3756 8.3872 5.0704 20.0609
MDA-MB-157 CTRP2 5.9582 8.2884 5.7343 15.8972
HCC1954 CTRP2 6.3669 13.2602 4.0321 21.2637
ZR-75-1 CTRP2 6.5437 7.1498 6.5425 11.2197
MDA-MB-231 CTRP2 7.2102 8.9017 6.8815 7.9895
Hs 578Bst CTRP2 7.3024 11.8959 5.5757 13.0498
MDA-MB-468 CTRP2 7.4119 9.4152 6.8677 7.5143
CAL-85-1 CTRP2 7.4627 12.0659 5.6396 12.4309
ZR-75-30 CTRP2 7.4675 8.2855 7.3819 5.3683
HCC1500 CTRP2 7.4877 8.3862 7.3722 5.344
SK-BR-3 CTRP2 7.5067 8.7542 7.2541 5.7396
MCF-7 CTRP2 7.5678 8.7852 7.3051 5.3766
HMC-1-8 CTRP2 7.58 8.0159 7.5654 4.3679
HCC1419 CTRP2 7.6583 8.2727 7.5937 4.0244
T-47D CTRP2 7.7269 8.369 7.6372 3.662
MDA-MB-361 CTRP2 7.7281 8.3258 7.6531 3.5994
BT-474 CTRP2 7.7322 8.2872 7.6698 3.5256
CAMA-1 CTRP2 7.7333 8.2722 7.6756 3.5011
HCC2218 CTRP2 7.7962 8.577 7.631 3.4926
BT-549 CTRP2 7.8248 8.5709 7.6634 3.2894
HCC1428 CTRP2 8.0091 8.5314 7.8702 1.991
BT-20 CTRP2 8.06 9.3686 7.5127 3.3493
HCC1395 CTRP2 8.3052 15.5787 4.6173 14.7903
EFM-192A CTRP2 8.7724 34.5234 -4.4683 33.9492
HCC1806 CTRP2 9.6228 18.0842 4.4091 13.1864
JIMT-1 CTRP2 10.3907 21.1112 3.4885 15.1603
BT 239 CTRP2 4.7366 5.1584 4.7366 23.2433
BT 416 CTRP2 7.2163 9.2204 6.7546 8.4678
BT 498 CTRP2 7.4729 16.8709 3.2627 21.3637
BT 330 CTRP2 7.4733 8.1263 7.4298 5.1787
BT 228 CTRP2 7.4749 10.2652 6.5299 8.7346
BT 422 CTRP2 7.4967 14.4285 4.4996 16.9064
BT 216 CTRP2 7.4998 14.015 4.7078 16.0961
BT 131 CTRP2 7.5107 8.3849 7.3976 5.1827
BT147 CTRP2 7.5412 8.449 7.4085 5.0537
BT 139 CTRP2 7.5568 8.0703 7.5319 4.5578
BT 231 CTRP2 7.5568 8.4884 7.4111 4.9991
BT 286 CTRP2 7.6007 8.1773 7.5567 4.3329
BT 359 CTRP2 7.61 9.5428 7.0048 6.4728
BT 159 CTRP2 7.6174 12.6451 5.4925 12.6986
BT 172 CTRP2 7.6239 8.2057 7.5748 4.1971
BT 333 CTRP2 7.6289 8.112 7.6019 4.0854
BT 482 CTRP2 7.6443 8.5168 7.4943 4.4365
BT 504 CTRP2 7.6539 8.1025 7.6309 3.9053
BT 340 CTRP2 7.6764 8.0914 7.6571 3.7425
BT 440 CTRP2 7.7411 13.4857 5.1836 13.6935
BT 145 CTRP2 7.747 8.1207 7.728 3.2717
BT 112 CTRP2 7.7661 8.176 7.7372 3.1795
BT 444 CTRP2 7.7937 11.9641 5.9873 10.2811
BT164 CTRP2 7.7978 8.1576 7.7758 2.9441
BT 232 CTRP2 7.8025 8.4935 7.6717 3.3176
BT 224 CTRP2 8.06 8.8719 7.7577 2.3299
BT 179 CTRP2 8.1274 8.6771 7.9154 1.5259
BT 245 CTRP2 8.1391 9.2204 7.6565 2.5823
BT 328 CTRP2 8.4387 12.0245 6.5029 6.8522
BT 320 CTRP2 8.8623 12.3752 6.6569 5.4747
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.0904 10.2574 6.1593 11.1667
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-626 CTRP2 4.5312 5.1445 4.5312 24.6105
LN-229 CTRP2 4.5771 6.2023 4.5666 24.3397
SNU-466 CTRP2 4.6292 7.3158 4.5068 24.3748
CAS-1 CTRP2 4.6477 5.1707 4.6477 23.8346
D283 Med CTRP2 5.4483 7.5016 5.3575 18.8158
KALS-1 CTRP2 6.059 7.7337 5.9753 14.7277
KNS-81 CTRP2 6.4523 7.3532 6.4417 11.8597
SW1088 CTRP2 6.5316 7.9837 6.4373 11.6215
SF268 CTRP2 7.0014 8.5491 6.7899 8.9257
Hs 683 CTRP2 7.21 7.8967 7.1868 6.8595
GOS-3 CTRP2 7.2803 8.1748 7.2079 6.5645
42-MG-BA CTRP2 7.3537 9.5275 6.7582 8.1002
GaMG CTRP2 7.3692 8.2494 7.285 6.0161
SNU-1105 CTRP2 7.4364 8.0621 7.4032 5.3877
SNB-75 CTRP2 7.4371 9.0005 7.0776 6.6154
SF539 CTRP2 7.4796 8.537 7.3103 5.5995
M059K CTRP2 7.5256 8.1392 7.4838 4.8248
DBTRG-05MG CTRP2 7.5481 10.6297 6.4227 9.0077
SF126 CTRP2 7.5539 8.1155 7.5198 4.6093
ONS-76 CTRP2 7.5787 8.4931 7.433 4.8542
U-251MG CTRP2 7.587 8.2055 7.5346 4.4543
A-172 CTRP2 7.6615 8.3122 7.5851 4.0465
U-118MG CTRP2 7.6743 15.1722 4.2849 17.3382
DK-MG CTRP2 7.8053 8.2564 7.7588 2.9821
T98G CTRP2 7.8066 9.5366 7.1967 5.2235
SF295 CTRP2 7.8397 8.5663 7.6809 3.1812
TM-31 CTRP2 7.8451 8.5533 7.692 3.1236
CCF-STTG1 CTRP2 7.865 8.2676 7.8206 2.5783
YH-13 CTRP2 7.9956 9.258 7.5089 3.5051
Becker CTRP2 8.0784 9.4621 7.4828 3.4353
YKG-1 CTRP2 8.092 8.8716 7.7873 2.1357
U-87MG ATCC CTRP2 8.1435 9.241 7.65 2.6004
KG-1-C CTRP2 8.1913 8.9384 7.8423 1.6971
8-MG-BA CTRP2 8.2039 9.4516 7.5966 2.7032
Daoy CTRP2 8.2679 13.6091 5.5712 11.0522
KNS-42 CTRP2 8.2971 10.3468 7.2262 4.0805
GB-1 CTRP2 8.4938 13.9606 5.5806 10.5847
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2 6.4706 8.4188 6.255 12.4633
JHUEM-2 CTRP2 6.9289 24.7094 -1.1183 32.7623
HEC-50B CTRP2 7.1965 11.681 5.5817 13.2668
RL95-2 CTRP2 7.4714 11.7729 5.7918 11.7857
HEC-6 CTRP2 7.5657 8.1254 7.5306 4.5344
MFE-296 CTRP2 7.5841 8.2225 7.5269 4.4905
EN CTRP2 7.6039 8.047 7.5865 4.2184
HEC-108 CTRP2 7.6312 12.1238 5.7633 11.5548
HEC-1-A CTRP2 7.6505 8.2103 7.6027 4.0158
ESS-1 CTRP2 7.6697 8.1641 7.635 3.8413
EFE-184 CTRP2 7.6798 8.8647 7.3866 4.761
HEC-251 CTRP2 7.6884 8.2038 7.6456 3.7458
AN3-CA CTRP2 7.7112 8.5685 7.5451 4.0563
JHUEM-7 CTRP2 7.7563 8.3271 7.6833 3.4052
HEC-59 CTRP2 8.0058 9.5811 7.3589 4.107
JHUEM-3 CTRP2 8.0287 9.1245 7.6049 3.0334
MFE-319 CTRP2 8.1074 9.0784 7.699 2.4705
HEC-1-B CTRP2 8.2944 9.9672 7.4137 3.2986
JHUEM-1 CTRP2 12.0447 25.3325 2.6105 15.4245
Ishikawa (Heraklio) 02 ER- CTRP2 4.8444 5.1695 4.8444 22.5257
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCW CTRP2 6.824 8.7573 6.5247 10.4307
CAL-54 CTRP2 6.8745 8.6644 6.6125 9.9557
KMRC-3 CTRP2 7.3212 10.3414 6.3456 9.8514
UO-31 CTRP2 7.3284 8.4626 7.1737 6.5461
769-P CTRP2 7.5524 12.5273 5.4928 12.8374
SNU-1272 CTRP2 7.5753 8.8111 7.302 5.3687
KMRC-2 CTRP2 7.5961 8.0543 7.577 4.2763
RCC10RGB CTRP2 7.6074 8.098 7.5814 4.225
KMRC-1 CTRP2 7.7338 8.2947 7.6693 3.5231
OS-RC-2 CTRP2 7.7531 8.3159 7.6836 3.4132
786-O CTRP2 7.7843 8.5122 7.645 3.4704
TUHR10TKB CTRP2 7.8425 9.4107 7.2916 4.7499
ACHN CTRP2 8.0178 8.9808 7.6652 2.8078
VMRC-RCZ CTRP2 8.0278 9.3829 7.4767 3.5686
Caki-1 CTRP2 8.3914 9.934 7.5076 2.7292
A-498 CTRP2 8.4356 9.6521 7.6813 1.9301
Caki-2 CTRP2 8.4824 9.6249 7.7292 1.6568
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C2A CTRP2 4.4503 8.9838 3.8768 27.1307
OUMS-23 CTRP2 4.6082 5.0555 4.6082 24.0975
HT115 CTRP2 4.7013 5.1575 4.7013 23.4782
C2BBe1 CTRP2 4.7692 5.99 4.7671 23.0333
SNU-81 CTRP2 5.8529 8.1397 5.6597 16.4862
CCK-81 CTRP2 5.931 7.7809 5.8277 15.6482
RKO CTRP2 6.0441 16.5257 2.1437 28.0214
LoVo CTRP2 6.299 10.6169 5.2002 16.9889
SNU-C5 CTRP2 6.3772 7.7985 6.3072 12.5631
SNU-407 CTRP2 6.5262 7.9683 6.4348 11.6466
SW620 CTRP2 6.5632 8.2702 6.3996 11.6587
COLO201 CTRP2 6.6714 7.1405 6.6711 10.3667
MDST8 CTRP2 6.7933 8.8952 6.4405 10.836
SNU-61 CTRP2 6.9698 9.7823 6.2549 11.0865
HT-55 CTRP2 7.0259 11.3864 5.5621 13.7436
CW-2 CTRP2 7.0975 8.6313 6.8649 8.368
SNU-1033 CTRP2 7.1321 10.7072 5.9887 11.7574
SW48 CTRP2 7.2047 10.1844 6.3062 10.2926
NCI-H508 CTRP2 7.3853 11.0983 6.0422 10.9469
CL-11 CTRP2 7.4224 8.6251 7.2159 6.119
LS411N CTRP2 7.4484 8.2536 7.3702 5.4681
KM12 CTRP2 7.528 9.2942 7.0395 6.5335
LS123 CTRP2 7.5752 8.3787 7.4696 4.7273
COLO 678 CTRP2 7.6048 8.7906 7.3414 5.1357
SNU-C4 CTRP2 7.6311 8.0769 7.6109 4.0472
HT-29 CTRP2 7.6591 8.1016 7.6366 3.8688
RCM-1 [Human ESC] CTRP2 7.6597 8.1322 7.6312 3.8859
HCT 15 CTRP2 7.6652 8.2124 7.6181 3.9154
LS1034 CTRP2 7.6739 8.2151 7.6269 3.8569
LS180 CTRP2 7.6804 8.7012 7.4579 4.4782
HCT 116 CTRP2 7.6839 8.1788 7.647 3.7546
NCI-H716 CTRP2 7.6893 8.3905 7.5891 3.9505
SW948 CTRP2 7.7156 8.2478 7.6634 3.5987
SK-CO-1 CTRP2 7.737 8.806 7.4709 4.2783
GP2d CTRP2 7.7413 8.5111 7.5998 3.763
HCC-56 CTRP2 7.8351 8.5967 7.6632 3.2626
HCT 8 CTRP2 7.8505 8.4862 7.7254 2.9788
SW1417 CTRP2 7.8809 8.7625 7.6361 3.2527
SNU-503 CTRP2 8.2633 9.4935 7.625 2.4701
COLO205 CTRP2 8.2993 10.0736 7.3645 3.4959
SNU-C1 CTRP2 8.8324 16.6359 4.5171 14.1727
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP2 4.0291 6.3773 3.9879 28.0903
HuH-6 CTRP2 4.2865 6.2652 4.2642 30.3539
SNU-182 CTRP2 4.6126 5.6352 4.6122 24.0699
SNU-761 CTRP2 4.8488 6.1595 4.8447 22.5099
SNU-886 CTRP2 5.9989 7.6312 3.6239 0.5544
Hep-G2 CTRP2 6.2998 7.4875 6.2702 12.9389
Li-7 CTRP2 7.5118 20.7767 1.3478 26.7175
JHH-5 CTRP2 7.5776 12.3229 5.6166 12.2751
SNU-449 CTRP2 7.5856 9.8276 6.8458 7.1797
JHH-1 CTRP2 7.6272 8.0441 7.6119 4.0564
Hep 3B2.1-7 CTRP2 7.6633 8.1982 7.6197 3.9154
SNU-423 CTRP2 7.6861 8.2842 7.6206 3.8432
SNU-878 CTRP2 7.8183 11.2804 6.3488 8.7229
SK-HEP-1 CTRP2 7.8934 8.789 7.6365 3.22
HuH-1 CTRP2 7.9414 9.6611 7.2611 4.6543
JHH-4 CTRP2 8.139 9.9397 7.2974 4.0878
SNU-387 CTRP2 8.147 9.1807 7.6831 2.4547
PLC/PRF/5 CTRP2 8.2858 9.3318 7.7241 2.0123
SNU-475 CTRP2 8.3186 9.1972 7.8172 1.5629
JHH-6 CTRP2 8.3305 9.359 7.7461 1.8396
JHH-2 CTRP2 8.4299 11.2331 6.8908 5.2429
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 125 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DMS 79 CTRP2 3.7597 5.0999 3.7589 29.748
NCI-H1975 CTRP2 4.0339 5.0946 4.0338 27.9205
NCI-H1184 CTRP2 4.1262 5.8817 4.1168 27.3371
NCI-H1694 CTRP2 4.3494 5.2065 4.3493 25.8206
NCI-H69 CTRP2 4.438 5.2873 4.4379 29.1053
HCC1833 CTRP2 4.4654 6.0048 4.4589 25.0701
NCI-H1734 CTRP2 4.4738 5.8394 4.4709 25.0022
NCI-H292 CTRP2 4.6057 6.2851 4.5925 24.1584
SK-MES-1 CTRP2 4.6068 6.0287 4.602 24.1232
NCI-H1105 CTRP2 4.6151 5.2576 4.6151 24.0521
SW1271 CTRP2 4.6538 6.8686 4.5973 23.9848
NCI-H1838 CTRP2 4.6547 5.8188 4.6535 23.7925
COR-L95 CTRP2 4.6894 5.2669 4.6894 23.5574
NCI-H2087 CTRP2 4.7531 5.4952 4.7531 23.1335
NCI-H2085 CTRP2 4.8231 10.2199 3.8275 26.1707
NCI-H661 CTRP2 4.964 7.1982 4.8851 21.9973
NCI-H889 CTRP2 5.2362 6.7377 5.2192 19.975
HCC1171 CTRP2 5.3824 8.8347 4.9381 20.5232
Calu-6 CTRP2 5.4303 6.3901 5.4288 18.6313
EBC-1 CTRP2 5.4947 6.9444 5.4741 18.2665
NCI-H727 CTRP2 5.8287 7.5901 5.7522 16.2351
NCI-H1666 CTRP2 5.8656 7.868 5.7385 16.1666
NCI-H1435 CTRP2 5.9352 7.891 5.8092 15.6999
NCI-H1373 CTRP2 6.101 7.472 6.061 14.2975
NCI-H2106 CTRP2 6.1103 11.067 4.807 19.0063
COLO 699 CTRP2 6.114 7.7478 6.0322 14.3555
LCLC-97TM1 CTRP2 6.1216 7.9254 6.0043 14.4294
EPLC-272H CTRP2 6.3366 7.9971 6.2221 12.9897
NCI-H446 CTRP2 6.4655 7.7539 6.4103 11.9242
NCI-H2444 CTRP2 6.7481 7.2267 6.7476 9.8571
NCI-H2286 CTRP2 6.8411 9.4859 6.2519 11.4348
HCC1588 CTRP2 6.8543 7.8227 6.817 9.275
NCI-H196 CTRP2 7.0165 9.6359 6.3676 10.5186
HCC366 CTRP2 7.0189 8.6817 6.762 8.9798
NCI-H358 CTRP2 7.0599 9.1132 6.6369 9.3457
RERF-LC-Ad1 CTRP2 7.0658 9.5679 6.4481 10.0717
NCI-H2023 CTRP2 7.0956 9.6594 6.4378 10.0359
LXF 289 CTRP2 7.1489 9.5726 6.5307 9.5294
NCI-H1568 CTRP2 7.178 8.7027 6.925 7.9122
NCI-H520 CTRP2 7.1817 8.1101 7.1162 7.1958
HCC95 CTRP2 7.2078 11.1243 5.8618 12.0966
NCI-H1355 CTRP2 7.2097 11.8652 5.5044 13.5515
NCI-H1581 CTRP2 7.2324 8.0791 7.1784 6.8178
Lu-99 CTRP2 7.267 8.5677 7.0704 7.1099
NCI-H1155 CTRP2 7.2791 9.8227 6.548 9.1317
NCI-H2172 CTRP2 7.2953 8.5005 7.1247 6.8251
DV-90 CTRP2 7.296 8.7309 7.0403 7.1422
NCI-H1563 CTRP2 7.3603 8.8768 7.0498 6.9293
NCI-H1650 CTRP2 7.3931 11.3206 5.9411 11.3454
HCC2279 CTRP2 7.402 11.4325 5.8948 11.516
HCC15 CTRP2 7.4105 9.9286 6.6281 8.4863
NCI-H441 CTRP2 7.4255 9.085 7.029 6.8376
MOR/CPR CTRP2 7.4499 7.9723 7.4326 5.243
HOP-62 CTRP2 7.4664 8.5855 7.278 5.7589
NCI-H2228 CTRP2 7.4788 10.115 6.6056 8.4151
LCLC-103H CTRP2 7.4884 11.2447 6.0668 10.6128
NCI-H2126 CTRP2 7.4923 8.3694 7.3827 5.2918
SK-LU-1 CTRP2 7.4968 11.512 5.9434 11.104
RERF-LC-A1 CTRP2 7.5006 11.6391 5.8843 11.3393
HARA [Human squamous cell lung carcinoma] CTRP2 7.5121 11.0843 6.1672 10.1446
LOU-NH91 CTRP2 7.5171 8.5803 7.3342 5.403
NCI-H1299 CTRP2 7.5248 11.8519 5.8017 11.6272
HCC2108 CTRP2 7.5254 11.7346 5.86 11.3854
NCI-H1703 CTRP2 7.538 8.592 7.352 5.2767
NCI-H23 CTRP2 7.5469 8.5196 7.389 5.1107
EKVX CTRP2 7.5725 9.0615 7.1897 5.8199
COR-L105 CTRP2 7.5732 14.9524 4.3061 17.4742
NCI-H838 CTRP2 7.5961 8.103 7.5682 4.3068
NCI-H1944 CTRP2 7.5968 8.5998 7.4114 4.8858
DMS 273 CTRP2 7.5972 8.3595 7.4999 4.5501
HCC78 CTRP2 7.6001 8.6909 7.3782 5.0051
NCI-H226 CTRP2 7.6054 8.0954 7.5797 4.2374
NCI-H841 CTRP2 7.6065 13.2799 5.1676 14.043
LK2 CTRP2 7.6123 7.9784 7.6042 4.1305
NCI-H322 CTRP2 7.6163 8.0956 7.5915 4.1618
NCI-H2405 CTRP2 7.6165 11.1221 6.2448 9.5912
RERF-LC-MS CTRP2 7.6252 8.7392 7.3844 4.9132
NCI-H2122 CTRP2 7.6548 10.5411 6.5653 8.1775
ChaGo-K-1 CTRP2 7.7034 8.3487 7.6187 3.7994
Calu-3 CTRP2 7.7035 9.5294 7.1017 5.8539
RERF-LC-Ad2 CTRP2 7.7128 8.1148 7.6922 3.5051
DMS 114 CTRP2 7.7201 8.2536 7.6667 3.5734
NCI-H1651 CTRP2 7.7211 8.6339 7.5287 4.0931
NCI-H2196 CTRP2 7.7241 8.3101 7.6538 3.6086
NCI-H2081 CTRP2 7.7243 8.4218 7.6157 3.75
NCI-H1793 CTRP2 7.7253 10.0006 6.8948 6.6548
HOP-92 CTRP2 7.7361 8.91 7.4235 4.4698
NCI-H1395 CTRP2 7.7443 9.0266 7.3784 4.6301
NCI-H1339 CTRP2 7.7637 8.1688 7.7363 3.1903
NCI-H810 CTRP2 7.767 8.27 7.713 3.264
NCI-H647 CTRP2 7.7705 8.8141 7.5015 4.0706
VMRC-LCD CTRP2 7.7768 8.2842 7.7193 3.2119
NCI-H522 CTRP2 7.7795 8.4953 7.6466 3.4775
Lu-65 CTRP2 7.8056 8.4385 7.6966 3.2138
NCI-H2029 CTRP2 7.814 8.351 7.7377 3.0343
LUDLU-1 CTRP2 7.8529 8.5111 7.7177 3.0022
T3M-10 CTRP2 7.8568 8.6279 7.6721 3.1709
KNS-62 CTRP2 7.9152 8.9469 7.5838 3.3809
LC-1/sq-SF CTRP2 7.9315 8.5575 7.7796 2.5509
NCI-H524 CTRP2 7.9577 12.5427 5.842 10.5465
HCC4006 CTRP2 7.9623 9.9828 7.1209 5.1933
HCC1438 CTRP2 7.9646 8.4961 7.8404 2.2242
SHP-77 CTRP2 7.9871 14.5839 4.8477 14.5266
PC-14 CTRP2 7.9941 10.7795 6.753 6.6654
NCI-H1869 CTRP2 8.0065 8.764 7.7591 2.4476
NCI-H1915 CTRP2 8.0196 11.0575 6.6365 7.1011
NCI-H1792 CTRP2 8.0666 15.3069 4.5537 15.5088
HCC827 CTRP2 8.1065 11.6883 6.3961 7.9341
HCC2935 CTRP2 8.1169 9.4085 7.5433 3.1018
NCI-H2170 CTRP2 8.1557 9.5912 7.4858 3.2643
Sq-1 CTRP2 8.1627 10.6218 6.9768 5.3862
A-549 CTRP2 8.1704 12.202 6.1934 8.6573
NCI-H460 CTRP2 8.216 10.6594 7.0028 5.1732
SBC-5 CTRP2 8.2371 9.7872 7.4566 3.2269
NCI-H2030 CTRP2 8.2388 11.453 6.6251 6.715
NCI-H2110 CTRP2 8.2714 9.987 7.385 3.4623
NCI-H211 CTRP2 8.3859 14.9491 4.9986 13.1417
NCI-H1755 CTRP2 8.5077 11.2795 6.9292 4.9429
BEN CTRP2 8.5337 10.1957 7.4865 2.5765
HCC1195 CTRP2 8.5897 11.9255 6.672 5.8737
NCI-H650 CTRP2 8.6469 16.5745 4.3991 14.9641
NCI-H2342 CTRP2 8.6816 10.9139 7.2424 3.3469
HCC44 CTRP2 8.7789 15.9021 4.8404 13.0271
NCI-H1623 CTRP2 10.4816 12.2901 7.6321 0.3438
Hs 888.Lu CTRP2 7.832 8.7203 7.6059 3.4973
⏷ Show the Full List of 125 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 4.6114 7.1816 4.5098 24.4214
SNU-8 CTRP2 4.2572 4.9664 4.2572 26.434
COV434 CTRP2 5.0758 7.7425 4.9074 21.5649
OVK18 CTRP2 5.2545 6.3907 5.2512 19.807
A2780 CTRP2 6.0313 8.0979 5.8651 15.2035
OVCAR-4 CTRP2 6.2615 7.6563 6.2067 13.28
OVCAR-5 CTRP2 6.2756 7.2989 6.2617 13.0466
OC 314 CTRP2 6.3464 7.2411 6.3385 12.5555
OV7 CTRP2 6.6321 11.733 5.0167 16.8724
COV644 CTRP2 6.9996 8.2482 6.8819 8.5932
SNU-119 CTRP2 7.0604 10.677 5.9332 12.1555
ONCO-DG-1 CTRP2 7.1847 8.9141 6.8496 8.1826
FU-OV-1 CTRP2 7.1954 8.2954 7.0822 7.2761
SK-OV-3 CTRP2 7.2547 8.8424 6.9524 7.5939
IGROV-1 CTRP2 7.3193 8.6977 7.0779 6.9337
Caov-3 CTRP2 7.3553 16.6836 3.2531 21.6517
OVSAHO CTRP2 7.478 11.8909 5.7398 11.9854
OAW42 CTRP2 7.4783 8.0242 7.4552 5.074
DOV13 CTRP2 7.4858 8.4074 7.363 5.384
RMG-I CTRP2 7.508 11.8687 5.7781 11.7614
TYK-nu CTRP2 7.5184 10.9434 6.2419 9.8215
SNU-840 CTRP2 7.5281 8.6014 7.3378 5.3582
ES2 CTRP2 7.5283 8.0122 7.5107 4.7223
JHOC-5 CTRP2 7.5455 11.7268 5.8821 11.2497
MCAS CTRP2 7.5782 8.9461 7.2467 5.5788
Kuramochi CTRP2 7.5855 13.0504 5.2629 13.7024
JHOS-2 CTRP2 7.6063 8.1653 7.5656 4.2841
COV362 CTRP2 7.6118 8.939 7.2842 5.343
OVISE CTRP2 7.6131 8.1345 7.58 4.212
OAW28 CTRP2 7.6538 9.4285 7.1015 5.9732
EFO-27 CTRP2 7.7362 8.3006 7.67 3.5131
TOV-112D CTRP2 7.8604 9.6479 7.1929 5.117
OV-90 CTRP2 7.9649 8.7208 7.739 2.6297
EFO-21 CTRP2 8.0443 8.7386 7.8076 2.16
JHOM-1 CTRP2 8.2778 9.1895 7.7886 1.7562
OV56 CTRP2 8.3829 9.4946 7.7193 1.8605
OVCAR-8 CTRP2 8.6889 15.5757 4.9314 12.8362
HEY A8 CTRP2 9.3248 15.6103 5.4069 9.8294
OVTOKO CTRP2 9.7181 20.6182 3.2273 17.1382
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 4.7157 8.081 4.4342 24.3564
SYO-1 CTRP2 10.2184 23.3138 2.2735 19.2041
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 7.5285 19.7333 1.883 25.3265
Yamato-SS CTRP2 7.7901 9.4015 7.2461 5.0584
Rh41 CTRP2 4.1507 4.9351 4.1507 27.1429
TTC-709 CTRP2 4.6474 6.1968 4.6387 23.8658
TE 617.T CTRP2 4.6523 6.1789 4.6443 23.8309
TE 441.T CTRP2 4.6887 5.1238 4.6887 23.5621
Rh18 CTRP2 4.7404 5.23 4.7404 23.218
G-402 CTRP2 6.1309 7.7503 6.05 14.2399
Tm87-16 CTRP2 6.5555 7.8148 6.4967 11.3378
RKN CTRP2 6.8021 9.1124 6.3654 11.0989
A-204 CTRP2 7.013 10.4625 5.9873 12.052
RD CTRP2 7.4057 10.6141 6.296 9.8564
BT-12 CTRP2 7.4061 8.0241 7.3774 5.574
BT-16 CTRP2 7.4777 8.6542 7.2636 5.7824
SW982 CTRP2 7.5282 19.0945 2.2016 24.4615
MES-SA CTRP2 7.5664 8.035 7.5481 4.4709
Hs 729.T CTRP2 7.5742 8.0712 7.5504 4.4381
GCT CTRP2 7.5944 8.2695 7.5249 4.4667
G-401 CTRP2 7.6486 8.8906 7.3432 5.0137
SK-UT-1 CTRP2 7.6696 11.6165 6.049 10.2887
KYM-1 CTRP2 7.916 8.5806 7.7535 2.6947
HT-1080 CTRP2 8.1405 9.7035 7.4167 3.5845
SK-LMS-1 CTRP2 8.1766 10.5859 7.0065 5.2344
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 8.419 9.6648 7.6625 2.0359
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ACC-MESO-1 CTRP2 4.455 7.1146 4.3523 25.4655
NCI-H28 CTRP2 5.8655 8.2308 5.6492 16.4854
IST-Mes1 CTRP2 7.4915 11.9593 5.7184 12.0435
NCI-H2052 CTRP2 7.5332 12.6068 5.4361 13.1105
MPP 89 CTRP2 7.5979 8.4304 7.4763 4.6361
NCI-H2452 CTRP2 7.6305 8.5158 7.4799 4.5299
JL-1 CTRP2 7.6905 13.9872 4.8896 14.9747
MSTO-211H CTRP2 7.9103 11.933 6.105 9.5483
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 6.029 9.2914 5.4726 16.6637
LNCaP clone FGC CTRP2 7.7385 8.5151 7.5953 3.7882
PaCa-3 CTRP2 8.1255 8.7509 7.8774 1.688
DU145 CTRP2 8.1528 9.082 7.7373 2.2153
VCaP CTRP2 9.9735 11.7248 7.6329 0.5634
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 7.4925 7.9991 7.4743 4.9624
A-253 CTRP2 7.8775 8.8729 7.5818 3.4803
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-StC-K140 CTRP2 1.4329 4.075 -0.7786 5.4437
NUGC-3 CTRP2 5.2581 6.3454 5.2556 19.7805
SNU-620 CTRP2 5.9352 18.4592 1.0957 30.83
Fu97 CTRP2 6.4969 7.8353 6.4298 11.7567
SNU-719 CTRP2 6.5315 8.772 6.2041 12.4735
NUGC-4 CTRP2 6.5912 14.601 3.5928 22.2654
IM95 CTRP2 6.6518 9.4138 6.0845 12.5951
MKN74 CTRP2 6.7947 9.107 6.3596 11.1415
ECC10 CTRP2 7.3 8.9885 6.9401 7.5186
Hs 746.T CTRP2 7.3394 9.8017 6.6175 8.7023
ECC12 CTRP2 7.4405 9.7964 6.7197 8.0414
GSS CTRP2 7.5213 8.4966 7.37 5.255
SNU-601 CTRP2 7.5566 8.1628 7.5121 4.6279
SNU-5 CTRP2 7.586 8.2346 7.5257 4.4894
MKN45 CTRP2 7.5919 8.3757 7.4887 4.6075
SNU-216 CTRP2 7.6366 8.2696 7.571 4.1724
KE-39 CTRP2 7.6391 9.488 7.0591 6.1815
HuG1-N CTRP2 7.6601 8.4508 7.536 4.2336
SNU-1 CTRP2 7.7276 8.3386 7.6483 3.6185
AGS CTRP2 7.9217 9.2862 7.4265 4.0124
LMSU CTRP2 7.9271 8.7464 7.6896 2.9225
SH-10-TC CTRP2 7.9329 8.695 7.7192 2.7886
MKN7 CTRP2 8.0584 8.8968 7.7441 2.3899
OCUM-1 CTRP2 8.0633 9.2351 7.5818 6.5294
SNU-668 CTRP2 8.42 15.598 4.7023 14.2388
KATO III CTRP2 8.4364 10.1616 7.4295 2.9768
HGC-27 CTRP2 8.9907 14.6104 5.6486 9.4164
SNU-1077 CTRP2 7.724 10.2603 6.7668 7.1875
SNU-685 CTRP2 8.0282 8.9895 7.6706 2.762
SNG-M CTRP2 8.2202 11.0191 6.8265 5.9052
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C CTRP2 4.7267 5.1694 4.7267 23.3088
ML-1 [Human leukemia] CTRP2 7.1318 9.5845 6.5081 9.6632
SW579 CTRP2 7.2638 8.3439 7.1421 6.8527
CGTH-W-1 CTRP2 7.3707 10.1819 6.4694 9.2283
B-CPAP CTRP2 7.3956 11.4723 5.8694 11.6353
TT CTRP2 7.4321 8.3769 7.3148 5.7194
BHT-101 CTRP2 7.5312 17.1249 3.1869 21.4853
FTC-238 CTRP2 7.7424 8.0955 7.7276 3.2879
FTC-133 CTRP2 8.0392 8.7251 7.8091 2.1657
TT2609-C02 CTRP2 8.3644 10.318 7.2949 3.6681
8505C CTRP2 12.2999 29.1329 0.9447 19.5231
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-899 CTRP2 4.5833 6.3131 4.5681 24.3145
SNU-46 CTRP2 4.6166 6.9513 4.5479 24.2743
BHY CTRP2 4.6621 5.7919 4.6611 23.7424
YD-10B CTRP2 6.0806 7.7337 5.9986 14.5783
YD-8 CTRP2 6.4704 7.5586 6.4428 11.7968
SCC-25 CTRP2 6.7086 8.0398 6.6173 10.4332
SNU-1214 CTRP2 6.7248 9.7708 6.009 12.6961
CAL-33 CTRP2 7.3284 8.7763 7.0568 6.9891
SNU-1066 CTRP2 7.4238 11.9769 5.6479 12.4829
HSC-4 CTRP2 7.4896 8.1354 7.4456 5.072
SNU-1076 CTRP2 7.5298 8.0363 7.5086 4.7244
CAL-27 CTRP2 7.5605 8.2623 7.49 4.6957
BICR 31 CTRP2 7.6222 8.2586 7.5584 4.2616
BICR 6 CTRP2 7.6238 8.1959 7.5773 4.1884
HSC-3 CTRP2 7.6356 8.184 7.5931 4.0959
Detroit 562 CTRP2 7.6432 8.2762 7.5762 4.1336
SCC-9 CTRP2 7.6897 8.3199 7.6133 3.8594
FaDu CTRP2 7.702 8.6404 7.506 4.233
BICR 16 CTRP2 7.7174 8.3955 7.6177 3.7621
BICR 22 CTRP2 7.7461 8.2068 7.7079 3.3456
PE/CA-PJ49 CTRP2 7.7847 8.7128 7.5608 3.7987
HSC-2 CTRP2 7.7872 8.276 7.7332 3.1299
SNU-1041 CTRP2 7.8822 11.2923 6.3994 8.3771
PE/CA-PJ34 (clone C12) CTRP2 7.9042 8.5782 7.7425 2.7687
PE/CA-PJ15 CTRP2 8.1628 9.2971 7.6388 2.608
SCC-4 CTRP2 8.2918 9.6347 7.5777 2.6154
PE/CA-PJ41 (clone D2) CTRP2 8.2977 10.2467 7.2767 3.8673
BICR 56 CTRP2 8.4894 9.7305 7.6825 1.8379
BICR 18 CTRP2 9.3323 11.7025 7.3028 2.2053
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1376 CTRP2 3.2908 9.6648 2.3892 40.3112
JMSU-1 CTRP2 4.5975 5.0683 4.5975 24.1688
CAL-29 CTRP2 6.5839 8.2536 6.4268 11.4981
RT-4 CTRP2 7.2056 8.4312 7.051 7.36
5637 CTRP2 7.368 11.3984 5.8798 11.6547
RT-112 CTRP2 7.4497 10.5612 6.3633 9.4777
J82 CTRP2 7.4595 9.8048 6.7343 7.9358
639V CTRP2 7.4644 8.0273 7.4397 5.1721
BC-3C CTRP2 7.5017 9.1939 7.0585 6.5239
647V CTRP2 7.5147 8.1724 7.4641 4.9285
UM-UC-3 CTRP2 7.5261 10.3611 6.5324 8.6055
VM-CUB-1 CTRP2 7.5589 11.6708 5.9219 11.0557
SCaBER CTRP2 7.7598 8.5114 7.6194 3.6366
KU-19-19 CTRP2 7.7813 8.647 7.5859 3.7088
UM-UC-1 CTRP2 7.8401 9.2034 7.389 4.3552
T24 CTRP2 7.968 13.7501 5.248 12.9656
KMBC-2 CTRP2 8.0279 9.4251 7.456 3.6548
SW1710 CTRP2 8.2101 9.8808 7.3872 3.5707
HT-1197 CTRP2 8.5086 9.5954 7.7623 1.4809
TCCSUP CTRP2 9.8655 18.117 4.5735 12.1735
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.4387 20.5753 1.3854 26.7791

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